The U.S. Ambassador to Panama, John Feeley is said to have resigned from his post, claiming he can no longer serve U.S. President Donald Trump.
This story was updated to include comments from the Department of State.
Under Secretary of State Steve Goldstein confirmed he was aware of Mr Feeley's planned departure ahead of the president's alleged remarks on Thursday. In November, foreign service officer Elizabeth Shackelford, who worked in Nairobi for the USA mission to Somalia, quit, writing a letter slamming the administration for abandoning human rights policy and its "stinging disrespect" of the foreign service.
"John was born for the foreign service", said the USA official.
The US ambassador to Panama has resigned over differences with the Trump administration.
He remained busy under Trump.
The administration has been rocked by a series of high-profile exits - including Sean Spicer as press secretary, James Comey as Federal Bureau of Investigation director, Anthony Scaramucci as communications director and Steve Bannon as chief strategist- since Trump took office. Vice President Mike Pence visited the country back in August.
According to several reports, including a senior Democratic senator, Trump repeatedly called Haiti, El Salvador and African nations as "shithole countries" during a White House meeting with lawmakers on immigration reform. "Yesterday was only one. And there will be more".
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