giftedviz.com
giftedviz.com November 21, 2018


Common painkiller linked to an increased risk of heart problems

09 September 2018, 04:56 | Rodolfo Wallace

The relatively increased risk was seen across the board, including in people who took a lower dose as well as those with no existing history of cardiovascular disease.

Experts have analyzed the cardiovascular risks that come together with diclofenac compared to other non-steroidal anti-inflammatory drugs (NSAIDs).

"Treatment of pain and inflammation with NSAIDs", explain the authors, "may be worthwhile for some patients to improve quality of life despite potential side effects".

The latest research comes a year after a decade-long Danish study found ibuprofen, commonly sold as Nurofen and Advil, had been associated with a 31 per cent increased risk of cardiac arrest.

Are you anxious the medication you take could be impacting your overall health negatively?

There was an increased incidence of serious cardiovascular events among those who had taken diclofenac for one month.

Elon Musk smokes weed on Joe Rogan podcast
Musk and Rogan had been filming in California where marijuana is legal, although Musk had to ask for reassurance before indulging. Elon Musk participated in a wide-ranging interview for the Joe Rogan Experience podcast broadcast live Thursday night on YouTube.


Korean Leaders To Meet This Month About A 'Nuclear-Free Korean Peninsula'
Seoul and Pyongyang both want a declaration to formally end the 1950-53 Korean War, which ended in an armistice. In response, Trump tweeted his thanks to Kim for proclaiming "unwavering faith in President Trump ".


Former NFL Player Joseph Randle Charged With Rape
Since then, he was arrested at a casino, busted at his ex-girlfriend's home, and allegedly ripped a TV off the wall in jail. In February 2015, Randle was involved in domestic disturbance that included the mother of his child at a hotel in Wichita.


As it is used mostly to treat inflammations and pains, diclofenac, which is a non-steroidal anti-inflammatory drug, also known as NSAID, is broadly consumed all over the world.

Alongside heart attacks, the study links diclofenac to cardiovascular disease including arrhythmic heartbeats, ischemic stroke and heart failure. During the follow-up period, between 1996-2016, the scientists eliminated other risk factors for cardiovascular diseases in the subjects who participated in the study.

The adverse event rate among diclofenac initiators increased 50 percent compared with non-medication users, 20 percent compared with paracetamol or ibuprofen initiators and 30 percent compared with naproxen initiators.

But its cardiovascular risks compared with those of other traditional NSAIDs have never been examined in large randomized controlled trials, and current concerns about these risks make such trials unethical to conduct. The authors then compared the documented health issues that arose within 30 days in individuals given a course of diclofenac (1.3 million people) to those of 3.8 million people given ibuprofen, 291,490 given naproxen, 764,781 people given the non-NSAID pain reliever paracetamol, and 1.3 million people not prescribed any drug at all. "In conclusion, our data support that initiation of diclofenac poses a cardiovascular health risk, both compared with no use, paracetamol use, and use of other traditional NSAIDs", they state. Among patients at moderate baseline risk, corresponding figures were seven, seven, eight and 14 additional events, respectively, and for those at high baseline risk, corresponding numbers were 16, 10, one and 39 additional events, respectively.

However, researchers point out that, while the relative risk increased significantly, the overall risk was still pretty small. But even so, researchers say that the risk is not really justified.



Other News

Trending Now

Trump high court nominee on track with Senate hearing in last day
Judge Kavanaugh could have said that he has never fired someone because they are LGBT, if true, which he did not. The committee's hearings this week have been high on spectacle and, arguably, low on substance.

Cher to play Pittsburgh during upcoming tour
The multi-award-winning singer, actress and performer will be crossing the US for the first time in five years. Cher will bring her "Here We Go Again" tour to Columbus for a February 10 performance at Nationwide Arena.

Young Saint Lucian Killed by Dallas Police after entering the Wrong Apartment
Hall said investigators obtained a blood sample from the Officer to determine if she had been using drugs or alcohol. Reporters pressed the police chief about the officer's mental state when she entered the apartment at 1210 S.

Donald Trump tells supporters ‘it’s your fault’ if he gets impeached
Trump said numerous Senate Democrats whom Tester had helped elect "are attacking Judge Kavanaugh and looking like fools". Trump also said special counsel Robert Mueller should have wrapped up the inquiry a "long time ago".

Seattle’s Bird expected to wear protective mask for Game 5
Taurasi finished with 17 points, but the Mercury were unable to overcome losing the first two games of the series in Seattle. The Mercury had a 21-5 scoring run late in the third and into the fourth to turn a 10-point deficit into a six-point lead.

Russian and Syrian jets pound Idlib province after Tehran summit
Erdogan called on Putin and Rouhani to agree to a ceasefire in Idlib, saying such an accord would be a "victory" of their summit. Mr Erdogan called for a "truce" at a press conference after the talks. "Any attack on Idlib would result in a catastrophe.

Eagles hold off Falcons to begin title defense
Foles hit Zach Ertz for 18 yards on third-and-6 and Ajayi ran in a few plays later to put Philadelphia up 10-6. Philadelphia, the reigning Super Bowl champion , will be a tough out against everyone on its home turf.

Le’Veon Bell Seems Rattled By Steelers Teammates Blasting Him Over Holdout
Foster said. "Here's a guy who doesn't give a damn , so I guess we'll treat it as such". Sounds like Bell wasn't expecting this level of criticism from his teammates.

Governor declares state of emergency in NC as Tropical Storm Florence strengthens
The National Hurricane Center said Florence's maximum sustained winds Friday evening were estimated to be 65 miles per hour . East Coast this weekend as the storm swirls across the Atlantic, according to forecasters at the National Hurricane Center .

Nadal retires to send Del Potro into US Open final
He was visited by a trainer at the changeover after the match's seventh game and tape was applied below the joint. In the final when I beat Rafa and then Roger I was a kid then, but now I am much older'.